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Sunday 15 September 2019
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Greater certainty

EliA RF isotypes – greater certainty of diagnosis

Nephelometry and turbidimetry, the most common methods for testing for rheumatoid factor, cannot measure individual isotypes.25

EliA    test is able to measure individual isotypes for rheumatoid factor (Separately measuring RF IgM, IgA and IgG).26

In a study of 290 RA patients, 53% were positive for 3 or more antibodies28

The addition of RF IgM and RF IgA to CCP improves the specificity of testing – if all three are positive, specificity is 100%, and as such a diagnosis of rheumatoid arthritis is very likely.26,27

Sensitivity and specificity of mono- and multi-serology testing EliA, in 190 RA patients and 197 disease controls.26