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Sunday 20 October 2019
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Hope for cancer cell "anchors"

Research that may prevent cancer cells spreading through the body is to be presented at the National Cancer Research Institute conference in Birmingham.

It centres on integrins, which anchor both healthy and cancer cells their 'home' tissue or organ and which can be destabilised by faults in the p53 protein.

Faulty p53 switches on the Rab-coupling protein (RCP) pathway cell-signalling system, which interferes with the normal delivery route of integrins to the cell's surface.