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Tuesday 26 March 2019
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Topic: Latest News

March 21, 2019
Scientists at the University of Surrey and University College London have revealed an innovative in vitro method that can help to develop easy to swallow medicine for children and older people
In an article published by the European Journal of Pharmaceutical Sciences, scientists compared traditional sensory tests and a new in vitro method that was able to explain why smaller multiparticulates eased the travel of medicine from the mouth into the throat and body, reducing mouth residue.
 
The test let scientists easily screen different compositions of the carrier liquid and concentration of the particulates, in order to make swallowing as easy as possible.
 
March 20, 2019
One in four people with coeliac disease were previously misdiagnosed with IBS

With only 3% of British adults aware that the symptoms of IBS (irritable bowel syndrome) are also common symptoms of coeliac disease, Coeliac UK, is calling on greater awareness of the similarity of symptoms and urges anyone with IBS to ask their GP for a coeliac disease blood test, if they have not already had one.

March 20, 2019
Precision-Panc seeks to uncover the molecular profile of individual patients with pancreatic cancer, to learn more about the disease and to pave the way for patients entering clinical trials in a way that matches their tumour biology to the type of treatment

A groundbreaking pancreatic cancer trial, which aims to match patients with more targeted and effective treatment for their tumours, has successfully recruited its 100th patient.

Run by Precision-Panc, a research programme and clinical trials project led by the University of Glasgow with major funding from Cancer Research UK, the trial brings a precision medicine approach to pancreatic cancer treatment for the first time in the UK.

March 19, 2019
Study shows that Emergency Department Pharmacist Practitioners can combine traditional clinical pharmacy with more hands-on medical practice including being designated care providers

The first evaluation of pharmacists based in accident and emergency departments has concluded that with additional clinical skills, they are able to take on overall clinical responsibility for patients.

Daniel Greenwood, a PhD student from The University of Manchester, UK, studied the work of people they termed Emergency Department Pharmacist Practitioners (EDPPs) from 15 NHS Trusts across the UK over 10 days.

March 18, 2019
44-week UNIFI data presented for the first time during plenary session at 14th Congress of the European Crohn’s and Colitis Organisation
Janssen has announced new data from the Phase III UNIFI maintenance study. 
 
March 18, 2019
Professor Evelien Dekker discusses the rising burden of colorectal cancer in Europe and the need for consistent and successful screening programmes across the continent
Colorectal cancer is Europe’s second biggest cancer killer, claiming the lives of nearly 200,000 people across the continent each year. Current trends predict that the burden of colorectal cancer could increase by 12% by 2020, affecting 502,000 Europeans a year by 2020.1
 
March 18, 2019
The REPAIR study showed that treatment with macitentan was associated with significant improvement in RV function in patients with PAH
 
Actelion has announced an interim analysis from the Right vEntricular Remodeling in Pulmonary ArterIal hypeRtension (REPAIR) study of Opsumit® (macitentan) that shows treatment with macitentan in patients with pulmonary arterial hypertension (PAH) was associated with significant improvements in right ventricular (RV) function, including reversal of RV remodelling and reduced pulmonary vascular resistance (PVR). 
 
March 15, 2019
Research led by the Royal College of Surgeons in Ireland (RCSI) has been awarded €7m to investigate new treatments for Parkinson’s over three years.

Research led by the Royal College of Surgeons in Ireland (RCSI) has been awarded €7m to investigate new treatments for Parkin

March 7, 2019
A report commissioned by the European Biosafety Network was launched at a roundtable on preventing exposure to hazardous drugs in healthcare, held in the European Parliament in Brussels attended by MEPs, unions, employers, professional associations, representatives of Member States and the European Commission
A report commissioned by the European Biosafety Network has shed light on conditions in hospitals across the EU which are endangering the lives of nurses and pharmacists, other hospital staff, carers and patients.
 
The report was launched on 7 March at a roundtable on preventing exposure to hazardous drugs in healthcare, held in the European Parliament in Brussels attended by MEPs, unions, employers, professional associations, representatives of Member States and the European Commission. 
 
March 4, 2019
Napp Pharmaceuticals' Pelmeg, a pegfilgrastim biosimilar, has been launched in the UK following its European Commission approval in November 2018
Napp Pharmaceuticals has announced the UK launch of Pelmeg®, a biosimilar of pegfilgrastim, following European Commission (EC) approval in November 2018.  
 
March 4, 2019
CHMP recommends Dupixent® (dupilumab) for use in adults and adolescents 12 years and older as add on maintenance treatment for certain forms of severe asthma
The European Medicines Agency’s
Committee for
March 4, 2019
Substantial data have been published since the last Scientific Statement in 2005 showing the importance of measuring blood pressure outside of the clinic setting
The accurate measurement of blood pressure is essential for the diagnosis and management of hypertension, a major risk factor for heart disease and stroke, according to an updated American Heart Association scientific statement on blood pressure measurement in humans, published in the American Heart Association journal Hypertension.
 
March 4, 2019
Iron deficiency anaemia is frequently seen in inflammatory bowel disease and is difficult to treat, partly because many patients are intolerant to traditional oral iron therapies
Shield Therapeutics and Norgine have announced positive results from the AEGIS Head-to-Head (H2H) clinical trial, which compared Feraccru® (ferric maltol), a novel oral iron replacement therapy, to Ferinject® (ferric carboxymaltose (FCM)), a market-leading intravenously delivered iron replacement therapy.1
 
March 4, 2019
Randomised clinical trial demonstrates safety and efficiency of a common and simplified protocol for pacemaker and defibrillator surveillance based on remote monitoring only
Two-year data from the RM-ALONE Trial1 evaluating the safety and workflow efficiency of remote cardiac monitoring with remote interrogations were recently published in the European Heart Journal.
 
The authors analysed the efficacy of Biotronik Home Monitoring® as a follow-up method after the implantation of cardiac implantable electronic devices (CIEDs) without regular in-person evaluations with a physician. 
 
February 28, 2019
NHS prescriptions are set to rise by 20p per item from 1 April 2019, the Government has announced

NHS prescriptions are set to rise by 20p per item from 1 April 2019, the Government announced on Thursday (21 February).

The raise from £8.80 to £9 will apply to each medicine or appliance dispensed, while the cost of prescription pre-payment certificates (PPC) has been frozen for a year at £29.10 for a three-month PPC and £104 for a 12-month PPC.

PPCs are available for patients who require four or more items in three months or more than 12 in a year.

February 28, 2019
The Department of Health and Social Care (DHSC) will spend around £11m on warehouse contracts to store medicines as a contingency measure for a no-deal Brexit, Hospital Healthcare Europe understands.

The Department of Health and Social Care (DHSC) will spend around £11m on warehouse contracts to store medicines as a contingency measure for a no-deal Brexit, Hospital Healthcare Europeunderstands.

In October last year, health and social care secretary Matt Hancock told the Health and Social Care Committee that the Government had issued an invitation to tender for additional storage space to stockpile medicines.

February 27, 2019
The largest study ever to look at why an expensive and commonly used group of drugs fails in patients with Crohn’s disease has concluded that standardised drug doses are often too low

A UK-wide collaboration led by the University of Exeter and the Royal Devon & Exeter NHS Foundation Trust, part-funded by Crohn’s & Colitis UK and Guts UK, and supported by the NIHR has concluded that trials are needed to investigate whether early personalised dosing, guided by blood level monitoring, might help reduce the rate of treatment failure.

February 26, 2019
A genetic discovery could make treatment for Crohn’s disease and ulcerative colitis safer, by identifying patients who are at risk of potentially deadly drug side effects

A ground-breaking and large-scale NHS research collaboration, led by the University of Exeter and the Royal Devon & Exeter NHS Foundation Trust, has discovered a gene mutation that allows the identification of patients at risk of a drug side effect, allowing clinicians to tailor alternative treatments to these individuals.

February 25, 2019
Deleting a specific gene in mice alleviates arthritis symptoms and could be used to formulate a cure in humans, researchers have found.

Deleting a specific gene in mice alleviates arthritis symptoms and could be used to formulate a cure in humans, researchers have found.

Researchers at the University of Virginia School of Medicine found that deleting a gene called ELMO1 in mice reduced inflammation in acute and chronic arthritis models.1

This was particularly surprising because the researchers had hypothesised that deleting the gene would worsen inflammatory arthritis because it promotes cytoskeletal reorganisation during engulfment.

February 21, 2019
Manufacturers may have to rethink the way they transport stock to avoid ‘at least’ six months of border delays in a no-deal Brexit, a letter from a health minister has warned.

Manufacturers may have to rethink the way they transport stock to avoid ‘at least’ six months of border

February 18, 2019
People with COPD need more support when understanding and acting on new chest symptoms, a study in the journal Psycho-Oncology reports

During a unique study, led by the University of Glasgow and University of Surrey, researchers have investigated how the experience of COPD influences how individuals understand new or changing chest symptoms and their decision to seek help from medical professionals. 

February 6, 2019
Pharmacists in the UK have been urged caution when dispensing the drug Amoxicillin by manufacturer Accord

Pharmacists in the UK have been urged caution when dispensing the drug Amoxicillin by manufacturer Accord.

The class 4 drug alert has been issued by the Medicines and Healthcare products Regulatory Agency (MHRA) for Amoxicillin 500mg capsules. The relevant batch numbers are MP18062, MP18063, and MP18064, distributed in October last year.

Accord Healthcare Limited said important information about potentially life-threatening side effects was not added to the patient information leaflet for some batches.

January 31, 2019
The funding will support projects based in Birmingham, Newcastle and Edinburgh and is part of Innovate UK’s partnership with the third sector on health research projects, bringing direct benefits to both patients and UK businesses
 
Coeliac UK, the national charity for people who need to live gluten free, has combined forces with Innovate UK, the UK’s innovation agency, to drive improvements worth £750,000 in the food technology, diagnostics and digital care industries.
 
January 29, 2019
The supply of medicines will be prioritised over ‘vital food’ in the event of a no-deal Brexit, according to health secretary Matt Hancock.

The supply of medicines will be prioritised over "vital food" in the event of a no-deal Brexit, according to health secretary Matt Hancock.